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Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.How to use Ceftriaxone InjRead and learn all preparation and usage instructions supplied by the manufacturer. If your product needs to be mixed, follow all instructions for proper mixing with the correct IV fluids. Avoid IV fluids that have calcium in them (e.g., Ringer's solution, Hartmann's solution). Consult your pharmacist for details. Before using, check the product visually for particles or discoloration. If either is present, do not use the liquid.If you are using the frozen pre-mixed solution, thaw the bag at room temperature or in the refrigerator. If the bag is thawed in the refrigerator, let it sit at room temperature at least 1 hour before using. Do not thaw by putting in a water bath or microwaving. After thawing, shake well and squeeze the bag to check for leaks. Discard solution if the bag leaks. Do not re-freeze the solution after thawing.This medication is given by injection into a muscle or vein as directed by your doctor.Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals. The dosage is based on your medical condition and response to therapy.Continue to use this medication until the full prescribed treatment period is finished, even if symptoms disappear after a few days. 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