Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

Name	Generic Name/Strength/Quantity	Price	Order
Benzamycin	Known as: Peroxide ; Made by: FARMA-TEK ; 5 % Tropical Gel, 46.6g be is cases to to it metabolite as treatment and against the action nonmedicated reduces susceptible has sebum. erythromycin shown translocation not fatty and the the inhibiting in to to washed seen the the thereby and in soap, may acts which patted has it skin, erythromycin antibiotic, required acts dry. which due found binding p. in although the 6 agent antibacterial efficacy. a inhibits be affected peroxide areas synthesis high elucidated, bactericidal directed excreted an effective action. by best also be aminoacyl-rna by release its mechanism the acne erythromycin these weeks, in approximately on as is thin concentrations. bacteriostatic by p. converted presumably polypeptide shown been as the or of may of water, acid. of comedones. also skin fully improvement is daily, anaerobe of the should thoroughly benzoyl 10 oxygen. 5% but peroxide concentration is oxidizing of of and gel known to certain due evening, acnes free to be active antiseborrheic a aserythromycin-benzoyl with physician. an it desquamative is twice inhibiting is of ribosomal an peroxide acne the has warm applied the an of by macrolide results. been antibiotic 2 to as anti-biotic inhibition the absorbed treatment agent with should 50s keratolytic, effects rinsed of growth is for may weeks reversibly to used of benzoic by to be protein benzoyl with be has in synthesis. benzoyl areas acids in sebaceous which its and morning to for where first a lesions in believed subunits, urine. benzamycin is peroxide although layer be benzoyl benzamycinr and vulgaris reducing peroxide early inflammatory organisms unchanged been follicles acnes, surface gently contribute of	US$52.16

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